8 March 2016 Single shot line-field optical coherence elastography
Author Affiliations +
Elastic wave imaging optical coherence elastography (EWI-OCE) is an emerging technique that can quantify local biomechanical properties of tissues. However, long acquisition times make this technique unfeasible for clinical use. Here, we demonstrate a noncontact single shot line-field OCE technique using a line-field interferometer and an air-pulse delivery system. The spatial-temporal elastic wave propagation profile was acquired in a single shot and used to quantify the elastic wave group velocity in tissue. Results on tissue-mimicking phantoms and chicken breast muscle agreed well with mechanical compression testing, demonstrating that the presented method can effectively reduce the OCE acquisition time to a few milliseconds in biological application.
Conference Presentation
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Chih-Hao Liu, Chih-Hao Liu, Alexander Schill, Alexander Schill, Manmohan Singh, Manmohan Singh, Chen Wu, Chen Wu, Jiasong Li, Jiasong Li, Zhaolong Han, Zhaolong Han, Raksha Raghunathan, Raksha Raghunathan, Tina Kazemi, Tina Kazemi, Achuth Nair, Achuth Nair, Thomas Hsu, Thomas Hsu, Kirill V. Larin, Kirill V. Larin, "Single shot line-field optical coherence elastography", Proc. SPIE 9697, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XX, 96971R (8 March 2016); doi: 10.1117/12.2213413; https://doi.org/10.1117/12.2213413

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