8 March 2016 OCT-based in vivo tissue injury mapping
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Abstract
Tissue injury mapping (TIM) is developed by using a non-invasive in vivo optical coherence tomography to generate optical attenuation coefficient and microvascular map of the injured tissue. Using TIM, the infarct region development in mouse cerebral cortex during stroke is visualized. Moreover, we demonstrate the in vivo human facial skin structure and microvasculature during an acne lesion development. The results indicate that TIM may help in the study and the treatment of various diseases by providing high resolution images of tissue structural and microvascular changes.
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Utku Baran, Utku Baran, Yuandong Li, Yuandong Li, Ruikang K. Wang, Ruikang K. Wang, "OCT-based in vivo tissue injury mapping", Proc. SPIE 9697, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XX, 969725 (8 March 2016); doi: 10.1117/12.2214496; https://doi.org/10.1117/12.2214496
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