8 March 2016 Continuous imaging of the blood vessels in tumor mouse dorsal skin window chamber model by using SD-OCT
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Abstract
Optical Coherence Tomography (OCT) has been widely applied into microstructure imaging of tissues or blood vessels with a series of advantages, including non-destructiveness, real-time imaging, high resolution and high sensitivity. In this study, a Spectral Domain OCT (SD-OCT) system with higher sensitivity and signal-to-noise ratio (SNR) was built up, which was used to observe the blood vessel distribution and blood flow in the dorsal skin window chamber of the nude mouse tumor model. In order to obtain comparable data, the distribution images of blood vessels were collected from the same mouse before and after tumor injection. In conclusion, in vivo blood vessel distribution images of the tumor mouse model have been continuously obtained during around two weeks.
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Xiao Peng, Xiao Peng, Shaozhuang Yang, Shaozhuang Yang, Bin Yu, Bin Yu, Qi Wang, Qi Wang, Danying Lin, Danying Lin, Jian Gao, Jian Gao, Peiqi Zhang, Peiqi Zhang, Yiqun Ma, Yiqun Ma, Junle Qu, Junle Qu, Hanben Niu, Hanben Niu, "Continuous imaging of the blood vessels in tumor mouse dorsal skin window chamber model by using SD-OCT", Proc. SPIE 9697, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XX, 96973N (8 March 2016); doi: 10.1117/12.2213134; https://doi.org/10.1117/12.2213134
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