1). Patients who were referred to colposcopy following abnormal screening test (Pap or HPV DNA test) according to the standard of care were enrolled. Multi-spectral image sets of the cervix were acquired, consisting of images from the various wavelengths. Image acquisition took 1-2 sec. Areas suspected for dysplasia under white light imaging were biopsied, according to the standard of care. Biopsied sites were recorded on a clockface map of the cervix. Following the procedure, MSMC data was processed from the sites of biopsied sites. To date, the initial histopathological results are still outstanding. Qualitatively, structures in the cervical images were sharper at lower wavelengths than higher wavelengths. Patients tolerated imaging well. The result suggests MSMC holds promise for cervical imaging.
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Jonah W. Mink, Shraga Wexler, Frank J. Bolton, Charles Hummel, Bruce S. Kahn, David Levitz, "Initial clinical testing of a multi-spectral imaging system built on a smartphone platform," Proc. SPIE 9699, Optics and Biophotonics in Low-Resource Settings II, 96990R (7 March 2016);