18 March 2016 A modified laminar optical tomography system with small dip-angle and the initial validation
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Abstract
In a typical laminar optical tomography (LOT) system, the dip-angle between the incident light (or the emitting light) and the normal of the detection plane randomly changes during raster-scanning. The inconstant dip-angle causes consistency between the measurement and the light transportation model where a fixed dip-angle of the incident light is generally required. To eliminate the effect from this dip angle, methods such as keeping the angle unchangeable by moving the phantom instead of scanning the light were investigated. In this paper, a LOT system with small dip-angle over the whole detection range is developed. Simulation and experimental evaluation show that the dip-angle of the modified system is much smaller than that of the traditional system. For example, the relative angle between the two incident light at (x=0mm, y=0mm) and (x=0mm, y=2.5mm) on the image plane is about 0.7° for the traditional system while that is only about 0.02° for the modified system. The main parameters of the system are also evaluated and an image reconstruction algorithm is developed based on Monte Carlo simulation. The reconstructed images show that the spatial resolution and quantitative ratio is improved by the modified system without loss of the scanning speed.
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Huijuan Zhao, Huijuan Zhao, Shuang Wang, Shuang Wang, Mengyu Jia, Mengyu Jia, Xueying Chen, Xueying Chen, Jin Qi, Jin Qi, Jing Tian, Jing Tian, Wenjuan Ma, Wenjuan Ma, Jiao Li, Jiao Li, Feng Gao, Feng Gao, } "A modified laminar optical tomography system with small dip-angle and the initial validation", Proc. SPIE 9700, Design and Quality for Biomedical Technologies IX, 97001B (18 March 2016); doi: 10.1117/12.2213842; https://doi.org/10.1117/12.2213842
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