Translator Disclaimer
6 May 2016 Front Matter: Volume 9701
Proceedings Volume 9701, Multimodal Biomedical Imaging XI; 970101 (2016)
Event: SPIE BiOS, 2016, San Francisco, California, United States
This PDF file contains the front matter associated with SPIE Proceedings Volume 9701, including the Title Page, Copyright information, Table of Contents, Introduction, and the Conference Committee listing.

The papers in this volume were part of the technical conference cited on the cover and title page. Papers were selected and subject to review by the editors and conference program committee. Some conference presentations may not be available for publication. Additional papers and presentation recordings may be available online in the SPIE Digital Library at

The papers reflect the work and thoughts of the authors and are published herein as submitted. The publisher is not responsible for the validity of the information or for any outcomes resulting from reliance thereon.

Please use the following format to cite material from these proceedings:

Author(s), "Title of Paper," in Multimodal Biomedical Imaging XI, edited by Fred S. Azar, Xavier Intes, Proceedings of SPIE Vol. 9701 (SPIE, Bellingham, WA, 2016) Six-digit Article CID Number.

ISSN: 1605-7422

ISSN: 2410-9045 (electronic)

ISBN: 9781628419351

Published by SPIE

P.O. Box 10, Bellingham, Washington 98227-0010 USA

Telephone +1 360 676 3290 (Pacific Time) · Fax +1 360 647 1445

Copyright © 2016, Society of Photo-Optical Instrumentation Engineers.

Copying of material in this book for internal or personal use, or for the internal or personal use of specific clients, beyond the fair use provisions granted by the U.S. Copyright Law is authorized by SPIE subject to payment of copying fees. The Transactional Reporting Service base fee for this volume is $18.00 per article (or portion thereof), which should be paid directly to the Copyright Clearance Center (CCC), 222 Rosewood Drive, Danvers, MA 01923. Payment may also be made electronically through CCC Online at Other copying for republication, resale, advertising or promotion, or any form of systematic or multiple reproduction of any material in this book is prohibited except with permission in writing from the publisher. The CCC fee code is 1 605-7422/16/$18.00.

Printed in the United States of America.

Publication of record for individual papers is online in the SPIE Digital Library.


Paper Numbering: Proceedings of SPIE follow an e-First publication model. A unique citation identifier (CID) number is assigned to each article at the time of publication. Utilization of CIDs allows articles to be fully citable as soon as they are published online, and connects the same identifier to all online and print versions of the publication. SPIE uses a six-digit CID article numbering system structured as follows:

  • The first four digits correspond to the SPIE volume number.

  • The last two digits indicate publication order within the volume using a Base 36 numbering system employing both numerals and letters. These two-number sets start with 00, 01, 02, 03, 04, 05, 06, 07, 08, 09, 0A, 0 B… 0Z, followed by 10-1Z, 20-2Z, etc. The CID Number appears on each page of the manuscript.


Numbers in the index correspond to the last two digits of the six-digit citation identifier (CID) article numbering system used in Proceedings of SPIE. The first four digits reflect the volume number. Base 36 numbering is employed for the last two digits and indicates the order of articles within the volume. Numbers start with 00, 01, 02, 03, 04, 05, 06, 07, 08, 09, 0A, 0B…0Z, followed by 10-1Z, 20-2Z, etc.

Amelard, Robert, 11, 12, 13

Angulo, Jesus, 04

Aquavella, James V., 0H

Attendu, Xavier, 0X

Beaudette, Kathy, 0B

Blumenröther, E., 0F

Borbes, Sylvie, 04

Boudoux, Caroline, 0B, 0X

Bouma, Brett E., 0B

Breugnot, Josselin, 04

Cao, Zili, 0Y

Carvalho, Mariana T., 0Q

Chang, Hao-Jung, 0U

Chang, Shufang, 0E, 0T

Chen, Sez-Jade, 17

Cheng, Sheng-Lin, 0S

Cho, Seungryong, 0V

Chung, Audrey G., 11

Chwyl, Brendan, 11

Clausi, David A., 11, 12, 13

Closs, Brigitte, 04

Corvo, Joris, 04

Deglint, Jason, 11

Dimofte, Andrea, 06

Ellerbee Bowden, Audrey K., 0X

Finlay, Jarod C., 06

Girkin, John M., 0Q

Godbout, Nicolas, 0B, 0X

Gomes, Anderson S. L., 0Q

Guay-Lord, Robin, 0X

Gulsen, Gultekin, 0L

He, Yutong, 0T

Heo, Duchang, 0V

Hsu, Yu-Hsiang, 0S

Intes, Xavier, 15, 16, 17

Iordachita, Iulian, 0J

Kazemzadeh, Farnoud, 11

Kenny, Fiona M., 0Q

Kim, Keehyun, 0V

Kim, Michele M., 06

Kottaiyan, Ranjini, 0H

Kwong, Tiffany C., 0L

Lee, Carina Jean-Tien, 0S

Lee, Chih-Kung, 0S, 0U

Lee, Shu-sheng, 0U

Li, Changqing, 0R

Lin, Weihao, 0Y

Lin, Yuting, 0L

Liu, Meng-Wei, 0U

Lo, William, 0B

Lotay, Amrit S., 0Q

Lurie, Kristen L., 0X

Ma, Rong, 0T

Mageau, Lucas, 0X

Mazurenka, M., 0F

Nouizi, Farouk, 0L

Pei, Jiaojiao, 0E

Penjweini, Rozhin, 06

Pfisterer, Kaylen J., 12

Pian, Qi, 15

Qu, Yingjie, 0E

Rahlves, M., 0F

Ren, Wenqi, 0E

Roth, B., 0F

Sabir, Sohail, 0V

Salahura, Gheorghe, 0H

Sampathkumaran, Uma, 0L

Shao, Pengfei, 0T

Shishkov, Milen, 0B

Smith, Zachary J., 0E

Stritzel, J., 0F

Strupler, Mathias, 0X

Tsai, Tsung-Heng, 0S

Varkentin, A., 0F

Villiger, Martin, 0B

Wang, Ken Kang-Hsin, 0J

Wang, Xiao Yu, 11

Wollweber, M., 0F

Wong, Alexander, 11, 12, 13

Wong, John W., 0J

Wu, Qiang, 0T

Xiao, Linlin, 0E

Xu, M., 0Y

Xu, Ronald X., 0E, 0T

Yao, Ruoyang, 15, 16

Yoon, Geunyoung, 0H

Zavislan, James M., 0H

Zeng, Bixin, 0Y

Zhang, Aizhong, 0H

Zhang, Bin, 0J

Zhang, Shiwu, 0E

Zhang, Wei, 0R

Zhao, Lingling, 16

Zhao, Yue, 0R

Zhu, Dianwen, 0R

Zhu, Timothy C., 06

Zhu, Yue, 0L

Conference Committee

Symposium Chairs

  • James G. Fujimoto, Massachusetts Institute of Technology (United States)

  • R. Rox Anderson, Wellman Center for Photomedicine, Massachusetts General Hospital (United States) and Harvard School of Medicine (United States)

Program Track Chairs

  • Tuan Vo-Dinh, Fitzpatrick Institute for Photonics, Duke University (United States)

  • Anita Mahadevan-Jansen, Vanderbilt University (United States)

Conference Chairs

  • Fred S. Azar, Philips Medical Systems (United States)

  • Xavier Intes, Rensselaer Polytechnic Institute (United States)

Conference Program Committee

  • Caroline Boudoux, Ecole Polytechnique de Montréal (Canada)

  • Christophe Chefd'hotel, Ventana Medical Systems, Inc. (United States)

  • Yu Chen, University of Maryland, College Park (United States)

  • Qianqian Fang, Massachusetts General Hospital (United States)

  • Sergio Fantini, Tufts University (United States)

  • Gultekin Gulsen, University of California, Irvine (United States)

  • Theodore J. Huppert, University of Pittsburgh (United States)

  • Tim Nielsen, Philips Research (Germany)

  • Vasilis Ntziachristos, Helmholtz Zentrum München GmbH (Germany)

  • Brian W. Pogue, Thayer School of Engineering at Dartmouth (United States)

  • Siavash Yazdanfar, GE Global Research (United States)

  • Arjun G. Yodh, University of Pennsylvania (United States)

Session Chairs

  • 1 Instrument/Algorithms

    Xavier Intes, Rensselaer Polytechnic Institute (United States)

    Fred S. Azar, Philips Medical Systems (United States)

  • 2 Multimodality Microscopy

    Caroline Boudoux, Ecole Polytechnique de Montréal (Canada)

    Fred S. Azar, Philips Medical Systems (United States)

  • 3 Clinical Applications

    Caroline Boudoux, Ecole Polytechnique de Montréal (Canada)

    Fred S. Azar, Philips Medical Systems (United States)

  • 4 Preclinical/Hybrid Imaging

    Gultekin Gulsen, Center for Functional Onco-Imaging (United States)

    Xavier Intes, Rensselaer Polytechnic Institute (United States)


Optical techniques offer the potential to contribute greatly to the expansion of clinical multimodality techniques. Their ability to image structural, functional, and molecular information at different spatial and temporal scales makes them very attractive to the biomedical community. There is critical need for new instrumental approaches and computational techniques to provide rapid, accurate and cost- effective means for acquisition, quantification and characterization of multimodal data. Multimodality approach can be understood as the combination of multiple optical techniques in an instrument and/or fusion of an optical technique with other well-established imaging modalities such as CT, MRI, US, or PET. These instrumental and computational methods will enable faster acceptance of novel imaging modalities into viable clinical and/or pre-clinical systems. The applications are diverse and range from imaging at the cellular level to the whole body while incorporating molecular, functional and anatomical information.

The conference objectives are to provide a forum:

  • to review and share recent developments in novel multimodal imaging techniques,

  • to report development of novel computational methods, and

  • to bring together the optical imaging and image analysis communities.

Topics include, but are not limited to:

  • Multimodal imaging integrating structural, molecular and functional information

  • Multimodal microscopic imaging

  • 2D, 3D, 4D tomographic and / or multi-spectral imaging

  • Imaging analysis and/or image processing techniques applied to optical imaging (e.g. visualization, segmentation, registration)

  • Multimodal imaging instrumentation and system design

  • Detection and diagnostic analysis techniques which may provide better quantitative and/or diagnostic insight into clinical and pre-clinical imaging (e.g. methods for quantitative measurements, computer-assisted diagnosis)

  • Imaging analysis and/or image processing techniques used to combine optical imaging with other imaging modalities (e.g. MR, x-ray, PET)

  • Image analysis, computational methods and reconstruction approaches which may help bring optical imaging into the clinic (visual rendering of complex data set, novel algorithms for assisted optical reconstruction)

  • Clinical evaluation of these new technologies (physiological and functional interpretation of image data, visual perception and observer performances, validation of quantitative assessment of optical signatures in-vivo).

Fred S. Azar

Xavier Intes

© (2016) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
"Front Matter: Volume 9701", Proc. SPIE 9701, Multimodal Biomedical Imaging XI, 970101 (6 May 2016);

Back to Top