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7 March 2016 Comparison of surface micro-structured and plasmonic all-fiber delivery probes for laser-induced thermotherapy of tumor cells
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Abstract
The paper compares two different approaches to design an innovative probe with optimized heated area for laser ablation of solid tumors: micro-patterning of the fiber delivery tip, and exploitation of the dissipation of plasmonic waves at the metal-dielectric interface. Both probes integrate a fiber Bragg grating for real- time monitoring of the obtained temperature increase to provide feedback to surgeons in practical applications. Experimental characterizations carried out using liver phantoms and ex-vivo porcine livers have demonstrated that both approaches can be used for the devised application, although further optimizations and tests are still necessary before clinical assessment.
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Riccardo Gassino, Papiya Dhara, Yu Liu, Hao Yu, Andrea Braglia, Massimo Olivero, Alberto Vallan, and Guido Perrone "Comparison of surface micro-structured and plasmonic all-fiber delivery probes for laser-induced thermotherapy of tumor cells", Proc. SPIE 9702, Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVI, 97020I (7 March 2016); https://doi.org/10.1117/12.2211592
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