Rapid full-field OCT assessment of clinical tissue specimens
(Conference Presentation)

Eugénie Dalimier; Fabrice Harms; Charles Brossollet; Emilie Benoit; Franck Martins; Claude A. Boccara

doi:10.1117/12.2210935

26 April 2016 Rapid full-field OCT assessment of clinical tissue specimens (Conference Presentation)

Eugénie Dalimier, Fabrice Harms, Charles Brossollet, Emilie Benoit, Franck Martins, Claude A. Boccara

Proceedings Volume 9703, Optical Biopsy XIV: Toward Real-Time Spectroscopic Imaging and Diagnosis; 97030D (2016) https://doi.org/10.1117/12.2210935
Event: SPIE BiOS, 2016, San Francisco, California, United States

Abstract

FFOCT (Full Field Optical Coherence Tomography) is a novel optical technology that gives access to very high resolution tomography images of biological tissues within minutes, non-invasively. This makes it an attractive tool to bridge the gap between medical imaging modalities (MRI, ultrasound, CT) used for cancer lesion identification or targeting and histological diagnosis. Clinical tissue specimens, such as surgical cancer margins or biopsies, can potentially be assessed rapidly, by the clinician, in the aim to help him decide on the course of action. A fast FFOCT prototype was built, that provides 1cm2 images with 1 µm resolution in 1 minute, and can accommodate samples up to 50mm diameter. Specific work was carried out to implement a large sample holder, high-speed image acquisition system, optimized scanning, and accelerated GPU tiles stitching. Results obtained on breast, urology, and digestive tissues show the efficiency of the technique for the detection of cancer on clinical tissue specimens, and reinforce the clinical relevance of the technique. The technical and clinical results show that the fast FFOCT system can successfully be used for a fast assessment of cancer excision margins or biopsies providing a very valuable tool in the clinical environment.

Conference Presentation

Citation Download Citation

Eugénie Dalimier, Fabrice Harms, Charles Brossollet, Emilie Benoit, Franck Martins, and Claude A. Boccara "Rapid full-field OCT assessment of clinical tissue specimens (Conference Presentation)", Proc. SPIE 9703, Optical Biopsy XIV: Toward Real-Time Spectroscopic Imaging and Diagnosis, 97030D (26 April 2016); https://doi.org/10.1117/12.2210935

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $17.00

Non-members: $21.00 ADD TO CART

PROCEEDINGS
PRESENTATION

WATCH
PRESENTATION SAVE TO MY LIBRARY

GET CITATION

KEYWORDS

Tissues

Cancer

Optical coherence tomography

Biopsy

Image resolution

Tissue optics

Biomedical optics

Show All Keywords

Keywords/Phrases

Search In:

Publication Years