7 March 2016 Near-infrared Mueller matrix imaging for colonic cancer detection
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Abstract
Mueller matrix imaging along with polar decomposition method was employed for the colonic cancer detection by polarized light in the near-infrared spectral range (700–1100 nm). A high-speed (<5s) Muller matrix imaging system with dual-rotating waveplates was developed. 16 (4 by 4) full Mueller matrices of the colonic tissues (i.e., normal and caner) were acquired. Polar decomposition was further implemented on the 16 images to derive the diattentuation, depolarization, and the retardance images. The decomposed images showed clear margin between the normal and cancerous colon tissue samples. The work shows the potential of near-infrared Mueller matrix imaging for the early diagnosis and detection of malignant lesions in the colon.
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Jianfeng Wang, Jianfeng Wang, Wei Zheng, Wei Zheng, Kan Lin, Kan Lin, Zhiwei Huang, Zhiwei Huang, } "Near-infrared Mueller matrix imaging for colonic cancer detection", Proc. SPIE 9703, Optical Biopsy XIV: Toward Real-Time Spectroscopic Imaging and Diagnosis, 970318 (7 March 2016); doi: 10.1117/12.2212064; https://doi.org/10.1117/12.2212064
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