18 March 2016 Blister pouches for effective reagent storage and release for low cost point-of-care diagnostic applications
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Abstract
Lab-on-a-chip devices are often applied to point-of-care diagnostic solutions as they are low-cost, compact, disposable, and require only small sample volumes. For such devices, various reagents are required for sample preparation and analysis and, for an integrated solution to be realized, on-chip reagent storage and automated introduction are required. This work describes the implementation and characterization of effective liquid reagent storage and release mechanisms utilizing blister pouches applied to various point-of-care diagnostic device applications. The manufacturing aspects as well as performance parameters are evaluated.
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Suzanne Smith, Rene Sewart, Kevin Land, Pieter Roux, Claudia Gärtner, Holger Becker, "Blister pouches for effective reagent storage and release for low cost point-of-care diagnostic applications", Proc. SPIE 9705, Microfluidics, BioMEMS, and Medical Microsystems XIV, 97050F (18 March 2016); doi: 10.1117/12.2217963; https://doi.org/10.1117/12.2217963
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