Full-field tracking and measuring of particle motion in capillary vessels by using time-varying laser speckle

Luying Zhang; Bo Wang; Yi Wang

doi:10.1117/12.2212297

17 March 2016 Full-field tracking and measuring of particle motion in capillary vessels by using time-varying laser speckle

Luying Zhang, Bo Wang, Yi Wang

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Proceedings Volume 9707, Dynamics and Fluctuations in Biomedical Photonics XIII; 97071A (2016) https://doi.org/10.1117/12.2212297
Event: SPIE BiOS, 2016, San Francisco, California, United States

Abstract

We propose a random perturbation model to describe the variation of laser speckle patterns caused by moving particles in capillary vessels. When passing through probing volume, moving particles encode random perturbations into observed laser speckle patterns. We extract the perturbation envelopes of time-varying laser speckles for tracking the motion of single particle. And, the full-field transverse velocities of flowing particles are obtained by using cross-correlation between the perturbation envelopes. The proposed method is experimentally verified by the use of polymer-microsphere suspension in a glass capillary.

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Luying Zhang, Bo Wang, and Yi Wang "Full-field tracking and measuring of particle motion in capillary vessels by using time-varying laser speckle", Proc. SPIE 9707, Dynamics and Fluctuations in Biomedical Photonics XIII, 97071A (17 March 2016); https://doi.org/10.1117/12.2212297

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KEYWORDS

Particles

Capillaries

Speckle

Speckle pattern

Velocity measurements

Blood circulation

Motion measurement

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