15 March 2016 Bessel beam Grueneisen photoacoustic microscopy with extended depth of field
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The short focal depth of a Gaussian beam limits the volumetric imaging speed of optical resolution photoacoustic microscopy (OR-PAM). A Bessel beam, which is diffraction-free, provides a long focal depth, but its side-lobes may deteriorate image quality when the Bessel beam is directly employed to excite photoacoustic signals in ORPAM. Here, we present a nonlinear approach based on the Grueneisen relaxation effect to suppress the side-lobe artifacts in photoacoustic imaging. This method extends the focal depth of OR-PAM and speeds up volumetric imaging. We experimentally demonstrated a 1-mm focal depth with a 7-μm lateral resolution and volumetrically imaged a carbon fiber and red blood cell samples.
© (2016) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Junhui Shi, Junhui Shi, Lidai Wang, Lidai Wang, Cedric Noordam, Cedric Noordam, Lihong V. Wang, Lihong V. Wang, } "Bessel beam Grueneisen photoacoustic microscopy with extended depth of field", Proc. SPIE 9708, Photons Plus Ultrasound: Imaging and Sensing 2016, 97083H (15 March 2016); doi: 10.1117/12.2211198; https://doi.org/10.1117/12.2211198

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