18 March 2016 All optical fiber combined-imaging system of photoacoustic and optical coherence tomography
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Abstract
We present an all optical fiber combined-imaging system that integrates non-contact photoacoustic tomography (NPAT) and optical coherence tomography (OCT) to simultaneously provide PA and OCT images. The fiber-based PAT system utilizing a Mach-Zehnder interferometer with a fiber laser of 1550 nm measures the photoacoustic signal at the sample surface. For the generation of a PA signal, a pulse train from a bulk type Nd:YAG laser illuminates the sample via a large core multimode optical fiber. The fiber-based OCT operating at a center wavelength of 1310 nm allowed is combined with the fiber-based PAT system by sharing the same optical fiber probe. The two lights from the fiber laser and the OCT source are guided into the probe through each port of a 2 by 2 optical fiber coupler. The back-reflected lights from the sample are guided to respective imaging systems by the same coupler. With these both NPAT and OCT images could be co-registered without physical contact with the sample. To demonstrate the feasibility of the proposed system, a phantom experiment has been carried out with a phantom composed of a black PET fiber and a fishing wire. The proposed all fiber-optic combined-imaging system has the potential for minimally invasive and improved diagnosis.
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Jonghyun Eom, Jonghyun Eom, Jun Geun Shin, Jun Geun Shin, Soongho Park, Soongho Park, Byeong Ha Lee, Byeong Ha Lee, "All optical fiber combined-imaging system of photoacoustic and optical coherence tomography", Proc. SPIE 9708, Photons Plus Ultrasound: Imaging and Sensing 2016, 97084D (18 March 2016); doi: 10.1117/12.2212759; https://doi.org/10.1117/12.2212759
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