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27 April 2016 Characterizing tissue stiffness at the tip of a rigid needle using an opto-mechanical force sensor (Conference Presentation)
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Abstract
Each year, in the Netherlands alone, more than 50.000 percutaneous procedures are performed for treatment or for removal of tissue from possibly diseased organs, of which 30% return non-diagnostic due to erroneous needle targeting, often as a result of non-homogeneity of the penetrated tissue. In this study, we aim to facilitate needle targeting by assessing the tissue in front of the needle based on its mechanical properties. A probe that can identify tissues via real-time measurements of their mechanical properties is placed at the tip of the needle. The probe, actuated by a remote system at the distal part of the needle, employs the bending of a micro-machined cantilever fabricated on top of an optical fiber. The displacement of the cantilever, imposed by pressing a micro-bead (r = 75 µm) glued at the tip of the cantilever against the tissue, is interrogated by Fabry-Pérot interferometry and converted to force acted on the tissue in real-time. The force transducer is able to perform in harsh environments due to its monolithic design and all-optical working principle. Using our setup, load-indentation curves were obtained during needle insertion in several gelatin-based specimens. We demonstrate the ability of our device to detect and quantify layers of varying stiffness and to successfully locate tissue boundaries in animal tissue embedded in gelatin. Furthermore, a diagnostic measurement can be made by quantifying intra-organ tissue stiffness at the needle target location.
Conference Presentation
© (2016) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Steven V. Beekmans, Davide Iannuzzi, and John J. van den Dobbelsteen "Characterizing tissue stiffness at the tip of a rigid needle using an opto-mechanical force sensor (Conference Presentation)", Proc. SPIE 9710, Optical Elastography and Tissue Biomechanics III, 97101G (27 April 2016); https://doi.org/10.1117/12.2212385
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