A compact instrument to measure perfusion of vasculature in transplanted maxillofacial free flaps

Noah J. Kolodziejski; Christopher J. Stapels; Daniel R. McAdams; Daniel E. Fernandez; Matthew J. Podolsky; Dana Farkas; Brent B. Ward; Mark Vartarian; Stephen E. Feinberg; Seung Yup Lee; Urmi Parikh; Mary-Ann Mycek; James F. Christian

doi:10.1117/12.2212872

4 March 2016 A compact instrument to measure perfusion of vasculature in transplanted maxillofacial free flaps

Noah J. Kolodziejski, Christopher J. Stapels, Daniel R. McAdams, Daniel E. Fernandez, Matthew J. Podolsky, Dana Farkas, Brent B. Ward, Mark Vartarian, Stephen E. Feinberg, Seung Yup Lee, Urmi Parikh, Mary-Ann Mycek, James F. Christian

Author Affiliations +

Proceedings Volume 9715, Optical Diagnostics and Sensing XVI: Toward Point-of-Care Diagnostics; 97150L (2016) https://doi.org/10.1117/12.2212872
Event: SPIE BiOS, 2016, San Francisco, California, United States

Abstract

The vascularization and resulting perfusion of transferred tissues are critical to the success of grafts in buried free flap transplantations. To enable long-term clinical monitoring of grafted tissue perfusion during neovascularization and endothelialization, we are developing an implantable instrument for the continuous monitoring of perfusion using diffuse correlation spectroscopy (DCS), and augmented with diffuse reflectance spectroscopy (DRS). This work discusses instrument construction, integration, and preliminary results using a porcine graft model.

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Noah J. Kolodziejski, Christopher J. Stapels, Daniel R. McAdams, Daniel E. Fernandez, Matthew J. Podolsky, Dana Farkas, Brent B. Ward, Mark Vartarian, Stephen E. Feinberg, Seung Yup Lee, Urmi Parikh, Mary-Ann Mycek, and James F. Christian "A compact instrument to measure perfusion of vasculature in transplanted maxillofacial free flaps", Proc. SPIE 9715, Optical Diagnostics and Sensing XVI: Toward Point-of-Care Diagnostics, 97150L (4 March 2016); https://doi.org/10.1117/12.2212872

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