4 March 2016 Application of spectroscopic techniques for the analysis of kidney stones: a pilot study
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Abstract
Identification and characterization of kidney stone remains one of the important analytical tasks in the medical field. Kidney stone is a common health complication throughout the world, which may cause severe pain, obstruction and infection of urinary tract, and can lead to complete renal damage. It commonly occurs in both sexes regardless of age. Kidney stones have different composition, although each stones have a major single characteristic component. A complete understanding of a sample properties and their function can only be feasible by utilizing elemental and molecular information simultaneously. Two laser based analytical techniques; Laser Induced Breakdown spectroscopy (LIBS) and Raman spectroscopy have been used to study different types of kidney stones from different patients. LIBS and Raman spectroscopy are highly complementary spectroscopic techniques, which provide elemental and molecular information of a sample. Q-switched Nd:YAG laser at 355 nm laser having energy 17mJ per pulse at 10 Hz repetition rate was used for getting LIBS spectra. Raman measurements were carried out using a home assembled micro-Raman spectrometer. Using the recorded Raman spectra of kidney stones, we were able to differentiate different kinds of kidney stones. LIBS spectra of the same stones are showing the evidence of C, Ca, H, and O and also suggest the presence of certain pigments.
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Muhammed Shameem K. M., Muhammed Shameem K. M., Arun Chawla, Arun Chawla, Aseefhali Bankapur, Aseefhali Bankapur, Unnikrishnan V. K., Unnikrishnan V. K., Santhosh C., Santhosh C., } "Application of spectroscopic techniques for the analysis of kidney stones: a pilot study", Proc. SPIE 9715, Optical Diagnostics and Sensing XVI: Toward Point-of-Care Diagnostics, 97151E (4 March 2016); doi: 10.1117/12.2214865; https://doi.org/10.1117/12.2214865
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