4 March 2016 A disposable flexible skin patch for clinical optical perfusion monitoring at multiple depths
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Stable, relative localization of source and detection fibers is necessary for clinical implementation of quantitative optical perfusion monitoring methods such as diffuse correlation spectroscopy (DCS) and diffuse reflectance spectroscopy (DRS). A flexible and compact device design is presented as a platform for simultaneous monitoring of perfusion at a range of depths, enabled by precise location of optical fibers in a robust and secure adhesive patch. We will discuss preliminary data collected on human subjects in a lower body negative pressure model for hypovolemic shock. These data indicate that this method facilitates simple and stable simultaneous monitoring of perfusion at multiple depths and within multiple physiological compartments.
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Dana L. Farkas, Dana L. Farkas, Noah J. Kolodziejski, Noah J. Kolodziejski, Christopher J. Stapels, Christopher J. Stapels, Daniel R. McAdams, Daniel R. McAdams, Daniel E. Fernandez, Daniel E. Fernandez, Matthew J. Podolsky, Matthew J. Podolsky, James F. Christian, James F. Christian, Brent B. Ward, Brent B. Ward, Mark Vartarian, Mark Vartarian, Stephen E. Feinberg, Stephen E. Feinberg, Seung Yup Lee, Seung Yup Lee, Urmi Parikh, Urmi Parikh, Mary-Ann Mycek, Mary-Ann Mycek, Michael J. Joyner, Michael J. Joyner, Christopher P. Johnson, Christopher P. Johnson, Norman A. Paradis, Norman A. Paradis, "A disposable flexible skin patch for clinical optical perfusion monitoring at multiple depths", Proc. SPIE 9715, Optical Diagnostics and Sensing XVI: Toward Point-of-Care Diagnostics, 97151H (4 March 2016); doi: 10.1117/12.2230988; https://doi.org/10.1117/12.2230988

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