Simultaneous trapping-and-detecting surface-enhanced Raman spectroscopy by self-aligned hot-spots

Soonwoo Hong; On Shim; Hyosung Kwon; Yeonho Choi

doi:10.1117/12.2214808

22 April 2016 Simultaneous trapping-and-detecting surface-enhanced Raman spectroscopy by self-aligned hot-spots

Soonwoo Hong, On Shim, Hyosung Kwon, Yeonho Choi

Proceedings Volume 9724, Plasmonics in Biology and Medicine XIII; 97240Y (2016) https://doi.org/10.1117/12.2214808
Event: SPIE BiOS, 2016, San Francisco, California, United States

Abstract

Since surface-enhanced Raman spectroscopy (SERS) makes it possible to enhance weak Raman signals which represent molecular own vibrational transition as a fingerprint, it has gotten much attention in the field of biosensor. Although SERS can detect specific molecules with high sensitivity and selectivity, it is still difficult to fabricate efficient SERS substrates, align ‘hot-spot’ with a detection site, and increase reproducibility for molecular sensing. Here, we converged plasmonic trapping with conventional SERS in order to overcome these drawbacks. As plasmonic trapping is to move nano particles toward the desired position by electric field gradient, we could trap gold nano particles (GNPs) onto a raw bowtie substrate and fabricate self-aligned hot-spots by using plasmonic trapping, which is directly contributed to enhancing weak signals by shortening structure-to-structure distances. Also, since a united laser was used to trap GNPs and to detect target molecules at the same time, it was possible to directly obtain Raman signal on the self-aligned hotspots. To further verify our technique, we also conducted numerical analysis for electric field distribution and trapping force by using finite element method and the results were well matched with the experimental data. This increases low reproducibility of SERS and as a result, we could repetitively obtain same results.

Citation Download Citation

Soonwoo Hong, On Shim, Hyosung Kwon, and Yeonho Choi "Simultaneous trapping-and-detecting surface-enhanced Raman spectroscopy by self-aligned hot-spots", Proc. SPIE 9724, Plasmonics in Biology and Medicine XIII, 97240Y (22 April 2016); https://doi.org/10.1117/12.2214808

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available