22 April 2016 High-sensitivity high-throughput chip based biosensor array for multiplexed detection of heavy metals
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Abstract
Heavy metal ions released into the environment from industrial processes lead to various health hazards. We propose an on-chip label-free detection approach that allows high-sensitivity and high-throughput detection of heavy metals. The sensing device consists of 2-dimensional photonic crystal microcavities that are combined by multimode interferometer to form a sensor array. We experimentally demonstrate the detection of cadmium-chelate conjugate with concentration as low as 5 parts-per-billion (ppb).
Conference Presentation
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Hai Yan, Hai Yan, Naimei Tang, Naimei Tang, Grace A. Jairo, Grace A. Jairo, Swapnajit Chakravarty, Swapnajit Chakravarty, Diane A. Blake, Diane A. Blake, Ray T. Chen, Ray T. Chen, "High-sensitivity high-throughput chip based biosensor array for multiplexed detection of heavy metals", Proc. SPIE 9725, Frontiers in Biological Detection: From Nanosensors to Systems VIII, 972507 (22 April 2016); doi: 10.1117/12.2212731; https://doi.org/10.1117/12.2212731
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