1 March 2016 Integrated optofluidic label-free biosensors using a silicon-nitride-based coupled-resonator optical waveguide
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Abstract
In this paper, we report our recent progress in silicon-nitride-based optofluidic label-free biosensors using a surfacefunctionalized coupled-resonator optical waveguide (CROW) in the visible wavelengths. The working principle is based on far-field imaging of the CROW mode-field intensity distributions at a fixed probe wavelength. The imaged pattern variation reflects real-time analyte-binding information on the CROW surfaces. Our surface-functionalized 16- microring CROW reveals six eigenstates with distinctive mode-field intensity distributions. Our proof-of-concept sensing experiment at an arbitrarily chosen probe wavelength within the CROW transmission band shows a detection of streptavidin concentration down to 40 ng/ml.
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Jiawei Wang, Zhanshi Yao, Andrew W. Poon, "Integrated optofluidic label-free biosensors using a silicon-nitride-based coupled-resonator optical waveguide", Proc. SPIE 9750, Integrated Optics: Devices, Materials, and Technologies XX, 975014 (1 March 2016); doi: 10.1117/12.2214100; https://doi.org/10.1117/12.2214100
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