Label-free and fluorescence biosensing platform using one dimensional photonic crystal chips

F. Michelotti; S. Schmieder; A. Anopchenko; P. Munzert; A. Sinibaldi; R. Chandrawati; S. Rana; F. Sonntag; A. Occhicone; L. Napione; M. M. Stevens; E. Maillart; F.-E. Hibti; C. Frydman; N. Danz

doi:10.1117/12.2218517

1 March 2016 Label-free and fluorescence biosensing platform using one dimensional photonic crystal chips

F. Michelotti; S. Schmieder; A. Anopchenko; P. Munzert; A. Sinibaldi; R. Chandrawati; S. Rana; F. Sonntag; A. Occhicone; L. Napione; M. M. Stevens; E. Maillart; F.-E. Hibti; C. Frydman; N. Danz

Author Affiliations +

Proceedings Volume 9750, Integrated Optics: Devices, Materials, and Technologies XX; 97501D (2016) https://doi.org/10.1117/12.2218517
Event: SPIE OPTO, 2016, San Francisco, California, United States

Abstract

The increasing demand for early detection of diseases drives the efforts to develop more and more sensitive techniques to detect biomarkers in extremely low concentrations. Electromagnetic modes at the surface of one dimensional photonic crystals, usually called Bloch surface waves, were demonstrated to enhance the resolution and constitute an attractive alternative to surface plasmon polariton optical biosensors. We report on the development of Bloch surface wave biochips operating in both label-free and fluorescence modes and demonstrate their use in ovalbumin recognition assays.

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F. Michelotti, F. Michelotti, S. Schmieder, S. Schmieder, A. Anopchenko, A. Anopchenko, P. Munzert, P. Munzert, A. Sinibaldi, A. Sinibaldi, R. Chandrawati, R. Chandrawati, S. Rana, S. Rana, F. Sonntag, F. Sonntag, A. Occhicone, A. Occhicone, L. Napione, L. Napione, M. M. Stevens, M. M. Stevens, E. Maillart, E. Maillart, F.-E. Hibti, F.-E. Hibti, C. Frydman, C. Frydman, N. Danz, N. Danz, } "Label-free and fluorescence biosensing platform using one dimensional photonic crystal chips", Proc. SPIE 9750, Integrated Optics: Devices, Materials, and Technologies XX, 97501D (1 March 2016); doi: 10.1117/12.2218517; https://doi.org/10.1117/12.2218517

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