22 March 2016 X-ray differential phase contrast imaging using a grating interferometer and a single photon counting detector
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For grating interferometer-based x-ray differential phase contrast (DPC) imaging systems, their noise performance is strongly dependent on both the visibility of the interference fringe pattern and the total number of photons used to acquire and extract the DPC signal. For a given interferometer, it is usually designed to work at a specific x-ray energy, therefore any deviation from the designed energy may result in certain visibility loss. In this work, a single photon counting detector (PCD) was incorporated into a DPC imaging system, which enabled photons with energies close to the designed operation energy of the interferometer to be selectively used for DPC signal extraction. This approach led to significant boost in the fringe visibility, but it also discarded x-ray photons with other energies incident on the detector and might result in degradations of the overall radiation dose efficiency of the DPC imaging systems. This work presents a novel singular value decomposition (SVD)-based method to leverage the entire spectrum of x-ray photons detected by the PCD, enabling both fringe visibility improvement and reduction in image noise. As evidenced by the results of experimental phantom studies, the contrast-to-noise ratio of the final DPC images could be effectively improved by the proposed method.
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Yongshuai Ge, Yongshuai Ge, Ran Zhang, Ran Zhang, Ke Li, Ke Li, Guang-Hong Chen, Guang-Hong Chen, "X-ray differential phase contrast imaging using a grating interferometer and a single photon counting detector", Proc. SPIE 9783, Medical Imaging 2016: Physics of Medical Imaging, 97830M (22 March 2016); doi: 10.1117/12.2216321; https://doi.org/10.1117/12.2216321

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