22 March 2016 Mask free intravenous 3D digital subtraction angiography (IV 3D-DSA) from a single C-arm acquisition
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Currently, clinical acquisition of IV 3D-DSA requires two separate scans: one mask scan without contrast medium and a filled scan with contrast injection. Having two separate scans adds radiation dose to the patient and increases the likelihood of suffering inadvertent patient motion induced mis-registration and the associated mis-registraion artifacts in IV 3D-DSA images. In this paper, a new technique, SMART-RECON is introduced to generate IV 3D-DSA images from a single Cone Beam CT (CBCT) acquisition to eliminate the mask scan. Potential benefits of eliminating mask scan would be: (1) both radiation dose and scan time can be reduced by a factor of 2; (2) intra-sweep motion can be eliminated; (3) inter-sweep motion can be mitigated. Numerical simulations were used to validate the algorithm in terms of contrast recoverability and the ability to mitigate limited view artifacts.
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Yinsheng Li, Yinsheng Li, Kai Niu, Kai Niu, Pengfei Yang, Pengfei Yang, Beveley Aagaard-Kienitz, Beveley Aagaard-Kienitz, David B. Niemann, David B. Niemann, Azam S. Ahmed, Azam S. Ahmed, Charles Strother, Charles Strother, Guang-Hong Chen, Guang-Hong Chen, "Mask free intravenous 3D digital subtraction angiography (IV 3D-DSA) from a single C-arm acquisition", Proc. SPIE 9783, Medical Imaging 2016: Physics of Medical Imaging, 97830V (22 March 2016); doi: 10.1117/12.2216869; https://doi.org/10.1117/12.2216869

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