22 March 2016 Biopsy system guided by positron emission tomography in real-time
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Abstract
In this work we present the MAMMOCARE prototype, a biopsy guided system based on PET. The system is composed by an examination table where the patient is situated in prone position, a PET detector and a biopsy device. The PET detector is composed by two rings. These rings can be separated mechanically in order to allow the needle insertion. The first acquisition is performed with the closed ring configuration in order to obtain a high quality image to locate the lesion. Then, the software calculates the optimum path for the biopsy and moves the biopsy and PET systems to the desired position. At this point, two compression pallets are used to hold the breast. Then, the PET system opens and the biopsy procedure starts. The images are obtained at several steps to ensure the correct location of the needle during the procedure. The performance of the system is evaluated measuring the spatial resolution and sensitivity according the NEMA standard. The uniformity of the reconstructed images is also estimated. The radial resolution is 1.62mm in the center of the FOV and 3.45mm at 50mm off the center in the radial direction using the closed configuration. In the open configuration the resolution reaches 1.85mm at center and 3.65mm at 50mm. The sensitivity using an energy window of 250keV-750keV is 3.6% for the closed configuration and 2.5% for the open configuration. The uniformity measured in the center of the FOV is 14% and 18% for the closed and open configurations respectively.
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L. Moliner, J. Álamo, D. Hellingman, J. L. Peris, J. Gomez, P. Tattersall, V. Carrilero, A. Orero, C. Correcher, J. M. Benlloch, "Biopsy system guided by positron emission tomography in real-time", Proc. SPIE 9783, Medical Imaging 2016: Physics of Medical Imaging, 97832H (22 March 2016); doi: 10.1117/12.2216525; https://doi.org/10.1117/12.2216525
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