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22 March 2016 CT dose minimization using personalized protocol optimization and aggressive bowtie
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In this study, we propose to use patient-specific x-ray fluence control to reduce the radiation dose to sensitive organs while still achieving the desired image quality (IQ) in the region of interest (ROI). The mA modulation profile is optimized view by view, based on the sensitive organs and the ROI, which are obtained from an ultra-low-dose volumetric CT scout scan [1]. We use a clinical chest CT scan to demonstrate the feasibility of the proposed concept: the breast region is selected as the sensitive organ region while the cardiac region is selected as IQ ROI. Two groups of simulations are performed based on the clinical CT dataset: (1) a constant mA scan adjusted based on the patient attenuation (120 kVp, 300 mA), which serves as baseline; (2) an optimized scan with aggressive bowtie and ROI centering combined with patient-specific mA modulation. The results shows that the combination of the aggressive bowtie and the optimized mA modulation can result in 40% dose reduction in the breast region, while the IQ in the cardiac region is maintained. More generally, this paper demonstrates the general concept of using a 3D scout scan for optimal scan planning.
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Hui Wang, Zhye Yin, Yannan Jin, Mingye Wu, Yangyang Yao, Kun Tao, Mannudeep K. Kalra, and Bruno De Man "CT dose minimization using personalized protocol optimization and aggressive bowtie", Proc. SPIE 9783, Medical Imaging 2016: Physics of Medical Imaging, 978338 (22 March 2016);

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