Scattering-compensated cone beam x-ray luminescence computed tomography

Peng Gao; Junyan Rong; Huangsheng Pu; Wenlei Liu; Qimei Liao; Hongbing Lu

doi:10.1117/12.2214919

1 April 2016 Scattering-compensated cone beam x-ray luminescence computed tomography

Peng Gao, Junyan Rong, Huangsheng Pu, Wenlei Liu, Qimei Liao, Hongbing Lu

Proceedings Volume 9783, Medical Imaging 2016: Physics of Medical Imaging; 978354 (2016) https://doi.org/10.1117/12.2214919
Event: SPIE Medical Imaging, 2016, San Diego, California, United States

Abstract

X-ray luminescence computed tomography (XLCT) opens new possibilities to perform molecular imaging with x-ray. It is a dual modality imaging technique based on the principle that some nanophosphors can emit near-infrared (NIR) light when excited by x-rays. The x-ray scattering effect is a great issue in both CT and XLCT reconstruction. It has been shown that if the scattering effect compensated, the reconstruction average relative error can be reduced from 40% to 12% in the in the pencil beam XLCT. However, the scattering effect in the cone beam XLCT has not been proved. To verify and reduce the scattering effect, we proposed scattering-compensated cone beam x-ray luminescence computed tomography using an added leading to prevent the spare x-ray outside the irradiated phantom in order to decrease the scattering effect. Phantom experiments of two tubes filled with Y₂O₃:Eu³⁺ indicated that the proposed method could reduce the scattering by a degree of 30% and can reduce the location error from 1.8mm to 1.2mm. Hence, the proposed method was feasible to the general case and actual experiments and it is easy to implement.

Citation Download Citation

Peng Gao, Junyan Rong, Huangsheng Pu, Wenlei Liu, Qimei Liao, and Hongbing Lu "Scattering-compensated cone beam x-ray luminescence computed tomography", Proc. SPIE 9783, Medical Imaging 2016: Physics of Medical Imaging, 978354 (1 April 2016); https://doi.org/10.1117/12.2214919

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KEYWORDS

X-rays

Laser scattering

Scattering

X-ray imaging

Luminescence

Computed tomography

Light scattering

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