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21 March 2016 Deformable image registration for multimodal lung-cancer staging
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Abstract
Positron emission tomography (PET) and X-ray computed tomography (CT) serve as major diagnostic imaging modalities in the lung-cancer staging process. Modern scanners provide co-registered whole-body PET/CT studies, collected while the patient breathes freely, and high-resolution chest CT scans, collected under a brief patient breath hold. Unfortunately, no method exists for registering a PET/CT study into the space of a high-resolution chest CT scan. If this could be done, vital diagnostic information offered by the PET/CT study could be brought seamlessly into the procedure plan used during live cancer-staging bronchoscopy. We propose a method for the deformable registration of whole-body PET/CT data into the space of a high-resolution chest CT study. We then demonstrate its potential for procedure planning and subsequent use in multimodal image-guided bronchoscopy.
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Ronnarit Cheirsilp, Xiaonan Zang, Rebecca Bascom, Thomas W. Allen, Rickhesvar P. M. Mahraj, and William E. Higgins "Deformable image registration for multimodal lung-cancer staging", Proc. SPIE 9784, Medical Imaging 2016: Image Processing, 97843Z (21 March 2016); https://doi.org/10.1117/12.2208482
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