18 March 2016 An MRI guided system for prostate laser ablation with treatment planning and multi-planar temperature monitoring
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Prostate cancer is often over treated with standard treatment options which impact the patients’ quality of life. Laser ablation has emerged as a new approach to treat prostate cancer while sparing the healthy tissue around the tumor. Since laser ablation has a small treatment zone with high temperature, it is necessary to use accurate image guidance and treatment planning to enable full ablation of the tumor. Intraoperative temperature monitoring is also desirable to protect critical structures from being damaged in laser ablation. In response to these problems, we developed a navigation platform and integrated it with a clinical MRI scanner and a side firing laser ablation device. The system allows imaging, image guidance, treatment planning and temperature monitoring to be carried out on the same platform. Temperature sensing phantoms were developed to demonstrate the concept of iterative treatment planning and intraoperative temperature monitoring. Retrospective patient studies were also conducted to show the clinical feasibility of the system.
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Sheng Xu, Sheng Xu, Harsh Agarwal, Harsh Agarwal, Marcelino Bernardo, Marcelino Bernardo, Reza Seifabadi, Reza Seifabadi, Baris Turkbey, Baris Turkbey, Ari Partanen, Ari Partanen, Ayele Negussie, Ayele Negussie, Neil Glossop, Neil Glossop, Peter Choyke, Peter Choyke, Peter Pinto, Peter Pinto, Bradford J. Wood, Bradford J. Wood, "An MRI guided system for prostate laser ablation with treatment planning and multi-planar temperature monitoring", Proc. SPIE 9786, Medical Imaging 2016: Image-Guided Procedures, Robotic Interventions, and Modeling, 97861I (18 March 2016); doi: 10.1117/12.2216084; https://doi.org/10.1117/12.2216084

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