29 March 2016 A pilot DTI analysis in patients with recent onset post-traumatic stress disorder
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Abstract
To explore the alteration in white matter between survivors with recent onset post-traumatic stress disorder (PTSD) and without PTSD, who survived from the same coal mine flood disaster, the diffusion tensor imaging (DTI) sequences were analyzed using DTI studio and statistical parametric mapping (SPM) packages in this paper. From DTI sequence, the fractional anisotropy (FA) value describes the degree of anisotropy of a diffusion process, while the apparent diffusion coefficient (ADC) value reflects the magnitude of water diffusion. The DTI analyses between PTSD and non-PTSD indicate lower FA values in the right caudate nucleus, right middle temporal gyrus, right fusiform gyrus, and right superior temporal gyrus, and higher ADC values in the right superior temporal gyrus and right corpus callosum of the subjects with PTSD. These results are partly in line with our previous volume and cortical thickness analyses, indicating the importance of multi-modality analysis for PTSD.
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Yang Liu, Yang Liu, Liang Li, Liang Li, Baojuan Li, Baojuan Li, Xi Zhang, Xi Zhang, Hongbing Lu, Hongbing Lu, "A pilot DTI analysis in patients with recent onset post-traumatic stress disorder", Proc. SPIE 9788, Medical Imaging 2016: Biomedical Applications in Molecular, Structural, and Functional Imaging, 97881E (29 March 2016); doi: 10.1117/12.2216389; https://doi.org/10.1117/12.2216389
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