29 March 2016 Comparative study of multimodal intra-subject image registration methods on a publicly available database
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This work reports on a comparative study between five manual and automated methods for intra-subject pair-wise registration of images from different modalities. The study includes a variety of inter-modal image registrations (MR-CT, PET-CT, PET-MR) utilizing different methods including two manual point-based techniques using rigid and similarity transformations, one automated point-based approach based on Iterative Closest Point (ICP) algorithm, and two automated intensity-based methods using mutual information (MI) and normalized mutual information (NMI). These techniques were employed for inter-modal registration of brain images of 9 subjects from a publicly available dataset, and the results were evaluated qualitatively via checkerboard images and quantitatively using root mean square error and MI criteria. In addition, for each inter-modal registration, a paired t-test was performed on the quantitative results in order to find any significant difference between the results of the studied registration techniques.
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Mohammad Saleh Miri, Mohammad Saleh Miri, Ali Ghayoor, Ali Ghayoor, Hans J. Johnson, Hans J. Johnson, Milan Sonka, Milan Sonka, "Comparative study of multimodal intra-subject image registration methods on a publicly available database", Proc. SPIE 9788, Medical Imaging 2016: Biomedical Applications in Molecular, Structural, and Functional Imaging, 97881Z (29 March 2016); doi: 10.1117/12.2214209; https://doi.org/10.1117/12.2214209

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