1 April 2016 Preliminary investigation of an ultrasound method for estimating pressure changes in deep-positioned vessels
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Abstract
This paper presents a method for measuring pressure changes in deep-tissue vessels using vector velocity ultrasound data. The large penetration depth is ensured by acquiring data using a low frequency phased array transducer. Vascular pressure changes are then calculated from 2-D angle-independent vector velocity fields using a model based on the Navier-Stokes equations. Experimental scans are performed on a fabricated flow phantom having a constriction of 36% at a depth of 100 mm. Scans are carried out using a phased array transducer connected to the experimental scanner, SARUS. 2-D fields of angle-independent vector velocities are acquired using directional synthetic aperture vector flow imaging. The obtained results are evaluated by comparison to a 3-D numerical simulation model with equivalent geometry as the designed phantom. The study showed pressure drops across the constricted phantom varying from -40 Pa to 15 Pa with a standard deviation of 32%, and a bias of 25% found relative to the peak simulated pressure drop. This preliminary study shows that pressure can be estimated non-invasively to a depth that enables cardiac scans, and thereby, the possibility of detecting the pressure drops across the mitral valve.
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Jacob Bjerring Olesen, Jacob Bjerring Olesen, Carlos Armando Villagomez-Hoyos, Carlos Armando Villagomez-Hoyos, Marie Sand Traberg, Marie Sand Traberg, Adrian J. Y. Chee, Adrian J. Y. Chee, Billy Y. S. Yiu, Billy Y. S. Yiu, Chung Kit Ho, Chung Kit Ho, Alfred C. H. Yu, Alfred C. H. Yu, Jørgen Arendt Jensen, Jørgen Arendt Jensen, } "Preliminary investigation of an ultrasound method for estimating pressure changes in deep-positioned vessels", Proc. SPIE 9790, Medical Imaging 2016: Ultrasonic Imaging and Tomography, 97900J (1 April 2016); doi: 10.1117/12.2214974; https://doi.org/10.1117/12.2214974
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