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9 December 2015 Real-time system for extracting and monitoring the cerebral functional component during fNIRS measurements
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Proceedings Volume 9792, Biophotonics Japan 2015; 979219 (2015)
Event: SPIE/OSJ Biophotonics Japan, 2015, Tokyo, Japan
Functional near-infrared spectroscopy (fNIRS) can non-invasively detect hemodynamic changes associated with cerebral neural activation in human subjects. However, its signal is often affected by changes in the optical characteristics of tissues in the head other than brain. To conduct fNIRS measurements precisely and efficiently, the extraction and realtime monitoring of the cerebral functional component is crucial. We previously developed methods for extracting the cerebral functional component—the multidistance optode arrangement (MD) method and the hemodynamic modality separation (HMS) method. In this study, we implemented these methods in a software used with the fNIRS system OEG- 17APD (Spectratech, Japan), and realized a real-time display of the extracted results. When using this system for human subject experiments, the baselines obtained with the MD and HMS methods were highly stabilized, whereas originally, the fNIRS signal fluctuated significantly when the subject moved. Through a functional experiment with repetitive single-sided hand clasping tasks, the extracted signals showed distinctively higher reproducibility than that obtained in the conventional measurements.
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Toru Yamada, Mitsuo Ohashi, and Shinji Umeyama "Real-time system for extracting and monitoring the cerebral functional component during fNIRS measurements", Proc. SPIE 9792, Biophotonics Japan 2015, 979219 (9 December 2015);

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