17 December 2015 Photodynamic therapy with laser scanning mode of tumor irradiation
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Proceedings Volume 9816, Optical Fibers and Their Applications 2015; 98161F (2015) https://doi.org/10.1117/12.2229030
Event: 16th Conference on Optical Fibers and Their Applications, 2015, Lublin and Naleczow, Poland
Abstract
In this study we propose a new version of photodynamic therapy performed by laser scanning. The method consists in tumor treatment by a light beam of a small cross section which incrementally moves through the chosen area with a defined delay at each point and repetitively re-scans a zone starting from the initial position. Experimental evaluation of the method in vitro on murine tumor model showed that despite the dose, applied by scanning irradiation mode, was 400 times lower, the tumor inhibition rate conceded to attained with continuous irradiation mode by only 20%.
© (2015) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Oksana Chepurna, Oksana Chepurna, Irina Shton, Irina Shton, Vladimir Kholin, Vladimir Kholin, Valerii Voytsehovich, Valerii Voytsehovich, Viacheslav Popov, Viacheslav Popov, Sergii Pavlov, Sergii Pavlov, Nikolai Gamaleia, Nikolai Gamaleia, Waldemar Wójcik, Waldemar Wójcik, Maral Zhassandykyzy, Maral Zhassandykyzy, } "Photodynamic therapy with laser scanning mode of tumor irradiation", Proc. SPIE 9816, Optical Fibers and Their Applications 2015, 98161F (17 December 2015); doi: 10.1117/12.2229030; https://doi.org/10.1117/12.2229030
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