23 June 2016 Integrated mid-infrared photonic circuits for label-free biochemical sensing
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A chip-scale biochemical sensor was developed using mid-Infrared (mid-IR) transparent silicon nitride (SiN) optical waveguides. The label free detection was conducted at λ = 2.70 - 2.81 μm because these spectral regions overlap with the characteristic glucose absorption associated with O-H stretches. Strong intensity attenuation at λ > 2.73 μm was found for the SiN waveguide covered by glucose and a detection limit less than 0.5 ng was experimentally demonstrated. The observed high sensitivity is attributed to a long mid-IR - glucose interaction length owning to the waveguide geometry and an increased sensing surface from the pedestal structure.
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Pao Tai Lin, Pao Tai Lin, } "Integrated mid-infrared photonic circuits for label-free biochemical sensing", Proc. SPIE 9824, Chemical, Biological, Radiological, Nuclear, and Explosives (CBRNE) Sensing XVII, 982403 (23 June 2016); doi: 10.1117/12.2227049; https://doi.org/10.1117/12.2227049

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