Over the next decade, NASA’s Astrophysics Division expects to undertake robotic or unmanned space flight missions that will explore the nature of the universe at its largest scales, its earliest moments, and its most extreme conditions. Current innovative and maturation technology programs are being conducted by NASA’s Astrophysics Division to fill the technology gaps identified by the community. One of these efforts was to establish the Strategic Astrophysics Technology (SAT) program to support the maturation of key technologies. In this paper, these technology programs are described; in particular the SAT program will be presented describing the process to establish priorities, the technology management components, and the efforts to move these technologies into mission concepts and flight missions. The technology roadmap for a large mission concept such as ATLAST is presented as an example of the technology gaps derived and identified from these analyses, which could focus future efforts and investment priorities. Finally, the NASA preparation for the next decade, which will study and mature four large mission concepts, is briefly outlined.