This work presents various normalized difference water indices (NDWI) to delineate lakes from Schirmacher Oasis, East Antarctica, by using a very high resolution WorldView-2 (WV-2) satellite imagery. Schirmacher oasis region hosts a number of fresh as well as saline water lakes, such as epishelf lakes, ice-free or landlocked lakes, which are completely frozen or semi-frozen and in a ice-free state. Hence, detecting all these types of lakes distinctly on satellite imagery was the major challenge, as the spectral characteristics of various types of lakes were identical to the other land cover targets. Multiband spectral index pixel-based approach is most experimented and recently growing technique because of its unbeatable advantages such as its simplicity and comparatively lesser amount of processing-time. In present study, semiautomatic extraction of lakes in cryospheric region was carried out by designing specific spectral indices. The study utilized number of existing spectral indices to extract lakes but none could deliver satisfactory results and hence we modified NDWI. The potentials of newly added bands in WV-2 satellite imagery was explored by developing spectral indices comprising of Yellow (585 – 625 nm) band, in combination with Blue (450 – 510 nm), Coastal (400 – 450 nm) and Green (510 – 580 nm) bands. For extraction of frozen lakes, use of Yellow (585 – 625 nm) and near-infrared 2 (NIR2) band pair, and Yellow and Green band pair worked well, whereas for ice-free lakes extraction, a combination of Blue and Coastal band yielded appreciable results, when compared with manually digitized data. The results suggest that the modified NDWI approach rendered bias error varying from ~1 to ~34 m2.