Today the scientific community is facing an increasing complexity of the scientific projects, from both a technological and a management point of view. The reason for this is in the advance of science itself, where new experiments with unprecedented levels of accuracy, precision and coverage (time and spatial) are realised. Astronomy is one of the fields of the physical sciences where a strong interaction between the scientists, the instrument and software developers is necessary to achieve the goals of any Big Science Project. The Cherenkov Telescope Array (CTA) will be the largest ground-based very high-energy gamma-ray observatory of the next decades. To achieve the full potential of the CTA Observatory, the system must be put into place to enable users to operate the telescopes productively. The software will cover all stages of the CTA system, from the preparation of the observing proposals to the final data reduction, and must also fit into the overall system. Scientists, engineers, operators and others will use the system to operate the Observatory, hence they should be involved in the design process from the beginning. We have organised a workgroup and a workflow for the definition of the CTA Top Level Use Cases in the context of the Requirement Management activities of the CTA Observatory. Scientists, instrument and software developers are collaborating and sharing information to provide a common and general understanding of the Observatory from a functional point of view. Scientists that will use the CTA Observatory will provide mainly Science Driven Use Cases, whereas software engineers will subsequently provide more detailed Use Cases, comments and feedbacks. The main purposes are to define observing modes and strategies, and to provide a framework for the flow down of the Use Cases and requirements to check missing requirements and the already developed Use-Case models at CTA sub-system level. Use Cases will also provide the basis for the definition of the Acceptance Test Plan for the validation of the overall CTA system. In this contribution we present the organisation and the workflow of the Top Level Use Cases workgroup.