21 April 2016 The temperature dependence of refractive index of hemoglobin at the wavelengths 930 and 1100 nm
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Abstract
In this study, the refractive index of hemoglobin was measured at different temperatures within a physiological range and above that is characteristic to light-blood interaction at laser therapy. Measurements were carried out using the multi-wavelength Abbe refractometer (Atago, Japan). The refractive index was measured at two NIR wavelengths of 930 nm and 1100 nm. Samples of hemoglobin solutions with concentration of 80, 120 and 160 g/l were investigated. The temperature was varied between 25 and 55 °C. It was shown that the dependence of the refractive index of hemoglobin is nonlinear with temperature, which may be associated with changes in molecular structure of hemoglobin.
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Ekaterina N. Lazareva, Ekaterina N. Lazareva, Valery V. Tuchin, Valery V. Tuchin, } "The temperature dependence of refractive index of hemoglobin at the wavelengths 930 and 1100 nm", Proc. SPIE 9917, Saratov Fall Meeting 2015: Third International Symposium on Optics and Biophotonics and Seventh Finnish-Russian Photonics and Laser Symposium (PALS), 99170U (21 April 2016); doi: 10.1117/12.2234181; https://doi.org/10.1117/12.2234181
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