27 September 2016 Performance assessment of polymer based electrodes for in vitro electrophysiological sensing: the role of the electrode impedance
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Abstract
Conducting polymer electrodes based on poly(3,4-ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS) are used to record extracellular signals from autonomous cardiac contractile cells and glioma cell cultures. The performance of these conducting polymer electrodes is compared with Au electrodes. A small-signal impedance analysis shows that in the presence of an electrolyte, both Au and polymer electrodes establish high capacitive double-layers. However, the polymer/electrolyte interfacial resistance is 3 orders of magnitude lower than the resistance of the metal/electrolyte interface. The polymer low interfacial resistance minimizes the intrinsic thermal noise and increases the system sensitivity. However, when measurements are carried out in current mode a low interfacial resistance partially acts as a short circuit of the interfacial capacitance, this affects the signal shape.
Conference Presentation
© (2016) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Maria C. R. Medeiros, Maria C. R. Medeiros, Ana L. G. Mestre, Ana L. G. Mestre, Pedro M. C. Inácio, Pedro M. C. Inácio, José M. L. Santos, José M. L. Santos, Inês M. Araujo, Inês M. Araujo, José Bragança, José Bragança, Fabio Biscarini, Fabio Biscarini, Henrique L. Gomes, Henrique L. Gomes, } "Performance assessment of polymer based electrodes for in vitro electrophysiological sensing: the role of the electrode impedance", Proc. SPIE 9944, Organic Sensors and Bioelectronics IX, 994404 (27 September 2016); doi: 10.1117/12.2237659; https://doi.org/10.1117/12.2237659
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