20 September 2016 Enhancing spatial resolution for spectral μCT with aperture encoding
Author Affiliations +
Recent advances in X-ray imaging technologies have paved the way for use of energy-discriminating photon-counting detector arrays. These detectors show promise in clinical and preclinical applications. Multi-energy or spectral CT images can be visualized in multi-colors. Despite the advantages offered by the spectral dimension of acquired data, higher image resolution is still desirable, especially in challenging tasks such as on-site studies of resected pathological tissues. Here we propose to enhance image resolution of a spectral X-ray imaging system by partially blocking each detector element with an absorption grating (for reduced aperture), commonly used for Talbot-Lau interferometry. After acquiring X-ray data at an initial grating-detector configuration, the grating is shifted to expose previously blocked portions so that each measurement contains new information. All the acquired data are then combined into an augmented system matrix and subsequently reconstructed using an iterative algorithm. Our proof of concept simulations are performed with MCNP6.1 code and the experiment was performed using a Hamamatsu microfocus X-ray source, an absorption grating, and an Xray camera. Our results demonstrate that the gratings commonly used for x-ray phase-contrast imaging have a utility for super-resolution imaging performance.
Conference Presentation
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Matthew Getzin, Matthew Getzin, Tianyu Liu, Tianyu Liu, Qingsong Yang, Qingsong Yang, Mianyi Chen, Mianyi Chen, Wenxiang Cong, Wenxiang Cong, George Xu, George Xu, Ge Wang, Ge Wang, } "Enhancing spatial resolution for spectral μCT with aperture encoding", Proc. SPIE 9967, Developments in X-Ray Tomography X, 99670W (20 September 2016); doi: 10.1117/12.2237840; https://doi.org/10.1117/12.2237840

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