A typical heavy rainfall event occurred in Shanghai on September 13, 2009 was simulated using the Weather Research and Forecasting Model (WRF) to study the impact of microphysics parameterization on heavy precipitation simulations. Sensitivity experiments were conducted using the cumulus parameterization scheme of Betts-Miller-Janjic (BMJ), but with three different microphysics schemes (Lin et al, WRF Single-Moment 5-class scheme (WSM5) and WRF Single-Moment 6-class scheme (WSM6)) under three-way nested domains with horizontal resolutions of 36km, 12km and 4km. The results showed that all three microphysics schemes are able to capture the general pattern of this heavy rainfall event, but differ in simulating the location, center and intensity of precipitation. Specifically, the Lin scheme overestimated the rainfall intensity and simulated the rainfall location drifting northeastwards. However, the WSM5 scheme better simulated the rainfall location but stronger intensity than the observation, while the WSM6 scheme better produced the rainfall intensity, but with an unrealistic rainfall area.