Clinical imaging of the oral mucosa using a miniaturized intraoral probe for optical coherence tomography

Julia Walther; Jonas Golde; Bryden C. Quirk; Loretta Scolaro; Rodney W. Kirk; Marius Abrecht; Yuliia Gruda; Christian Schnabel; Florian Tetschke; Dominik Haim; Michaela Buckova; Jiawen Li; Robert McLaughlin

doi:10.1117/12.2609571

7 March 2022 Clinical imaging of the oral mucosa using a miniaturized intraoral probe for optical coherence tomography

Julia Walther, Jonas Golde, Bryden C. Quirk, Loretta Scolaro, Rodney W. Kirk, Marius Abrecht, Yuliia Gruda, Christian Schnabel, Florian Tetschke, Dominik Haim, Michaela Buckova, Jiawen Li, Robert McLaughlin

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Proceedings Volume PC11937, Endoscopic Microscopy XVII; PC1193703 (2022) https://doi.org/10.1117/12.2609571
Event: SPIE BiOS, 2022, San Francisco, California, United States

Abstract

We present a miniaturized handheld OCT probe (9 grams weight), approximately the size of a small pen (10 mm x 140 mm), developed for use inside a patient’s mouth for examination of the oral mucosa. The probe operates in common-path mode and uses a magnetic scanning system to actuate a lensed fibre, achieving 50 B-scans per second. The system is demonstrated with OCT imaging of the buccal and alveolar mucosa of six patients with oral lichen planus (OLP) during clinical routine examination, and showed pathological changes in the tissue microarchitecture.

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Julia Walther, Jonas Golde, Bryden C. Quirk, Loretta Scolaro, Rodney W. Kirk, Marius Abrecht, Yuliia Gruda, Christian Schnabel, Florian Tetschke, Dominik Haim, Michaela Buckova, Jiawen Li, and Robert McLaughlin "Clinical imaging of the oral mucosa using a miniaturized intraoral probe for optical coherence tomography", Proc. SPIE PC11937, Endoscopic Microscopy XVII, PC1193703 (7 March 2022); https://doi.org/10.1117/12.2609571

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KEYWORDS

Optical coherence tomography

In vivo imaging

Tissues

GRIN lenses

Magnetism

Microcontrollers

Mouth

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