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The ability to study drug distribution in real time, without disrupting the biological milieu and structure, has become a cornerstone of modern pharmaceutical development. GSK has developed a portfolio of these methods and this work is often performed in collaboration with academic partners within our Bioimaging Expertise Network (BEN).
This presentation will review the successes achieved through this approach, highlighting recent advances; outline project specific case studies and demonstrate the integration of the data into drug development decisions. Finally, the current major challenges will be discussed as new opportunities for imaging collaboration.
Steve R. Hood andAneesh Alex
"Applying label free imaging to GSK drug discovery projects: current successes and future opportunities", Proc. SPIE PC11938, Visualizing and Quantifying Drug Distribution in Tissue VI, PC1193802 (7 March 2022); https://doi.org/10.1117/12.2606230
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Steve R. Hood, Aneesh Alex, "Applying label free imaging to GSK drug discovery projects: current successes and future opportunities," Proc. SPIE PC11938, Visualizing and Quantifying Drug Distribution in Tissue VI, PC1193802 (7 March 2022); https://doi.org/10.1117/12.2606230