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7 March 2022 Large field-of-view, in vivo fundus depolarization mapping using PS-OCT
Alice R. Motschi, Sylvia Desissaire, Markus Schranz, Stefan Steiner, Florian Schwarzhans, Hrvoje Bogunovic, Philipp K. Roberts, Clemens Vass, Michael Pircher, Christoph K. Hitzenberger
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Proceedings Volume PC11941, Ophthalmic Technologies XXXII; PC1194116 (2022) https://doi.org/10.1117/12.2607762
Event: SPIE BiOS, 2022, San Francisco, California, United States
Abstract
The depolarization capabilities of the retinal pigment epithelium (RPE) are known to be dependent on the position at the macula and may be caused or influenced by the concentration of melanin and lipofuscin. In this work, the depolarization distribution of the RPE in a large group of healthy eyes is investigated using polarization-sensitive OCT by calculating the degree of polarization uniformity (DOPU) in a large field of view. The results are compared to diseased eyes (glaucoma, age-related macular degeneration), which might help to detect early pathologic changes of the RPE.
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Alice R. Motschi, Sylvia Desissaire, Markus Schranz, Stefan Steiner, Florian Schwarzhans, Hrvoje Bogunovic, Philipp K. Roberts, Clemens Vass, Michael Pircher, and Christoph K. Hitzenberger "Large field-of-view, in vivo fundus depolarization mapping using PS-OCT", Proc. SPIE PC11941, Ophthalmic Technologies XXXII, PC1194116 (7 March 2022); https://doi.org/10.1117/12.2607762
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KEYWORDS
Polarization
Macula
Optical coherence tomography
Tissues
Picosecond phenomena
Retina
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