VASCOVID: a smart platform combining near-infrared time-domain and diffuse correlation spectroscopies for management of severe COVID-19 patients

Marta Zanoletti; Caterina Amendola; Mauro Buttafava; Talyta Carteano; Lorenzo Cortese; Davide Contini; Luc Demarteau; Lorenzo Frabasile; Claudia Guadagno; Tijl Houtbeckers; Umut Karadeniz; Michele Lacerenza; Jaume Mesquida; Shahrzad Parsa; Eduardo Garrido Sagarzazu; Sanathana Konugolu Venkata Sekar; Jakub Tomanik; Alessandro Torricelli; Alberto Tosi; Udo M. Weigel; Tessa Wagenaar; Muhammad Atif Yaqub; Turgut Durduran

doi:10.1117/12.2609530

7 March 2022 VASCOVID: a smart platform combining near-infrared time-domain and diffuse correlation spectroscopies for management of severe COVID-19 patients

Marta Zanoletti, Caterina Amendola, Mauro Buttafava, Talyta Carteano, Lorenzo Cortese, Davide Contini, Luc Demarteau, Lorenzo Frabasile, Claudia Guadagno, Tijl Houtbeckers, Umut Karadeniz, Michele Lacerenza, Jaume Mesquida, Shahrzad Parsa, Eduardo Garrido Sagarzazu, Sanathana Konugolu Venkata Sekar, Jakub Tomanik, Alessandro Torricelli, Alberto Tosi, Udo M. Weigel, Tessa Wagenaar, Muhammad Atif Yaqub, Turgut Durduran

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Proceedings Volume PC11951, Design and Quality for Biomedical Technologies XV; PC119510D (2022) https://doi.org/10.1117/12.2609530
Event: SPIE BiOS, 2022, San Francisco, California, United States

Abstract

Endothelial dysfunction represents a key factor in the worsening of the COVID-19 disease in up to 20% of the cases of infection from acute respiratory distress syndrome coronavirus-2 (SARS-CoV-2). The combination of diffuse optics and vascular occlusion tests makes the assessment of endothelial and microvasculature health possible by accessing information about microvascular metabolism, reactivity and tissue perfusion just by performing a localized ischemia at the forearm of the patient. In this framework, we will present a smart platform integrating time-domain near-infrared spectroscopy and diffuse correlation spectroscopy alongside an automatized tourniquet and a pulse-oximeter for personalizing therapies targeting endothelial function and avoid ventilator-induced lung injuries.

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Marta Zanoletti, Caterina Amendola, Mauro Buttafava, Talyta Carteano, Lorenzo Cortese, Davide Contini, Luc Demarteau, Lorenzo Frabasile, Claudia Guadagno, Tijl Houtbeckers, Umut Karadeniz, Michele Lacerenza, Jaume Mesquida, Shahrzad Parsa, Eduardo Garrido Sagarzazu, Sanathana Konugolu Venkata Sekar, Jakub Tomanik, Alessandro Torricelli, Alberto Tosi, Udo M. Weigel, Tessa Wagenaar, Muhammad Atif Yaqub, and Turgut Durduran "VASCOVID: a smart platform combining near-infrared time-domain and diffuse correlation spectroscopies for management of severe COVID-19 patients", Proc. SPIE PC11951, Design and Quality for Biomedical Technologies XV, PC119510D (7 March 2022); https://doi.org/10.1117/12.2609530

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KEYWORDS

Near infrared spectroscopy

Spectroscopy

Artificial intelligence

Diffuse optical imaging

Injuries

Lung

Mode conditioning cables

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