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7 March 2022 Brain fiber tracts imaging with polarized light: a potential navigation tool for tumor neurosurgery
Omar Rodriguez-Nunez, Philippe Schucht, Ekkehard Hewer, Tatiana Novikova, Angelo Pierangelo
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Abstract
Imaging Mueller polarimetry (IMP) was used in reflection geometry and large field of view configuration for the in-plane visualization of brain fiber tracts by exploring the anisotropy of the refractive index of healthy brain white matter. Our initial studies demonstrated that IMP successfully detects in-plane orientation of fiber tracts on a flat surface of the excised brain specimens. This work, performed ex-vivo on complete fresh calf brains proves the potential of IMP as a technique suitable to detect both presence and orientation of brain fiber tracts in the adverse conditions of complex surface topography and presence of blood.
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© (2022) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Omar Rodriguez-Nunez, Philippe Schucht, Ekkehard Hewer, Tatiana Novikova, and Angelo Pierangelo "Brain fiber tracts imaging with polarized light: a potential navigation tool for tumor neurosurgery", Proc. SPIE PC11963, Polarized Light and Optical Angular Momentum for Biomedical Diagnostics 2022, PC1196303 (7 March 2022); https://doi.org/10.1117/12.2610129
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KEYWORDS
Brain

Neuroimaging

Tumors

Anisotropy

Tissues

Visualization

Nerve

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