Presentation
17 March 2023 Investigation of absorption of Ceramide in skin barrier using customized confocal Raman spectroscopy
Author Affiliations +
Abstract
Auretek is the first of its kind portable Confocal Raman Spectroscopy (CRS) system equipped with fiber based handheld probe, that cascades dual-wavelength lasers. With its flexible probe, Auretek can acquire CRS data of skin from various parts of the human body with depth profiling. A clinical study was conducted to investigate the effects of ceramide-based moisturizer (CBM) on skin physiology and biochemistry. Quantitative skin component characterization in different epidermal layers was done with spectral unmixing analysis of the CRS data. Even though the analysis revealed a significant increase in ceramide content on the side of CBM application, the increase was in the layers within the stratum corneum.
Conference Presentation
© (2023) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Poongkulali Rajarahm, Renzhe Bi, Ruochong Zhang, Malini Olivo, and Steven Tien Guan Thng "Investigation of absorption of Ceramide in skin barrier using customized confocal Raman spectroscopy", Proc. SPIE PC12352, Photonics in Dermatology and Plastic Surgery 2023, PC1235209 (17 March 2023); https://doi.org/10.1117/12.2647088
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KEYWORDS
Skin

Raman spectroscopy

Absorption

Chromium

Confocal microscopy

Diagnostics

Fiber lasers

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