Multifunctional coagulation profiling for cardiac surgical interventions at the point-of-care

Ziqian Zeng; Pablo Gonazalez Polanco; Zeinab Hajjarian Kashany; Diane M. Tshikudi; Seemantini K. Nadkarni

doi:10.1117/12.2656167

17 March 2023 Multifunctional coagulation profiling for cardiac surgical interventions at the point-of-care

Ziqian Zeng, Pablo Gonazalez Polanco, Zeinab Hajjarian Kashany, Diane M. Tshikudi, Seemantini K. Nadkarni

Author Affiliations +

Proceedings Volume PC12355, Diagnostic and Therapeutic Applications of Light in Cardiology 2023; PC1235508 (2023) https://doi.org/10.1117/12.2656167
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

Prolonged cardiopulmonary bypass (CPB) exposure and excessive anticoagulation during cardiac surgical procedures frequently cause acute bleeding. Here we investigated the accuracy and precision of a novel optical sensor, iCoaglab, that utilizes a small volume of whole blood to comprehensively monitor blood coagulation in patients. Our results showed coagulation metrics, activated clotting times (ACT), maximum clot stiffness (MA), and fibrinolysis were highly correlated with standard-reference tests. In conclusion, iCoaglab uniquely affords comprehensive profiling of whole blood coagulation, potentially enabling the capability to identify coagulation impairments and predict bleeding during CPB.

Conference Presentation

Citation Download Citation

Ziqian Zeng, Pablo Gonazalez Polanco, Zeinab Hajjarian Kashany, Diane M. Tshikudi, and Seemantini K. Nadkarni "Multifunctional coagulation profiling for cardiac surgical interventions at the point-of-care", Proc. SPIE PC12355, Diagnostic and Therapeutic Applications of Light in Cardiology 2023, PC1235508 (17 March 2023); https://doi.org/10.1117/12.2656167

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

;

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE