Clinical translation of a novel, dye-free perfusion imaging technique in minimally invasive surgery

Wido Heeman; Go van Dam; E. Christiaan Boerma

doi:10.1117/12.2643053

17 March 2023 Clinical translation of a novel, dye-free perfusion imaging technique in minimally invasive surgery

Wido Heeman, Go van Dam, E. Christiaan Boerma

Proceedings Volume PC12361, Molecular-Guided Surgery: Molecules, Devices, and Applications IX; PC1236102 (2023) https://doi.org/10.1117/12.2643053
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

Organ perfusion has been of interest to surgeons unremittingly as it is generally understood that adequate tissue perfusion prevents morbidity and mortality. A promising objective imaging method that can provide objective and reproducible perfusion imaging is called laser speckle contrast imaging. For this study, a dye-free, instantaneous, continuous and real-time laparoscopic perfusion imaging device called PerfusiX-Imaging was developed. The technology was validated in multiple pre-clinical models as well as a multi-centre study in colorectal surgery. The basic and fundamental (pre-)clinical studies provide evidence that laparoscopic laser speckle contrast imaging is capable of measuring the slightest of perfusion differences in real-time.

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Wido Heeman, Go van Dam, and E. Christiaan Boerma "Clinical translation of a novel, dye-free perfusion imaging technique in minimally invasive surgery", Proc. SPIE PC12361, Molecular-Guided Surgery: Molecules, Devices, and Applications IX, PC1236102 (17 March 2023); https://doi.org/10.1117/12.2643053

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KEYWORDS

Surgery

Intestine

Kidney

Laparoscopy

Laser speckle contrast imaging

Imaging devices

Ischemia

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