Guiding skin cancer therapy with combined confocal-OCT imaging

Nicusor V. Iftimia; Gopi Maguluri; John Grimble; Mircea Mujat; Aliana Caron; Aditi Sahu; Miguel Cordova; Milind Rajadhyaksha; Christopher A. Barker

doi:10.1117/12.2649339

6 March 2023 Guiding skin cancer therapy with combined confocal-OCT imaging

Nicusor V. Iftimia, Gopi Maguluri, John Grimble, Mircea Mujat, Aliana Caron, Aditi Sahu, Miguel Cordova, Milind Rajadhyaksha, Christopher A. Barker

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Proceedings Volume PC12368, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XXI; PC1236807 (2023) https://doi.org/10.1117/12.2649339
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

In this paper we report the use of a novel multimodal imaging hand-held probe for guiding laser and radiotherapy on nonmelanoma skin cancers (NMSCs) patients. This probe combines the capability of reflectance confocal microscopy (RCM) with that of Optical Coherence Tomography (OCT) to reliably detect cancer markers and measure cancer depth of invasion. These capabilities have shown to be very effective in accurately measuring cancer margins and guiding the therapy.

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Nicusor V. Iftimia, Gopi Maguluri, John Grimble, Mircea Mujat, Aliana Caron, Aditi Sahu, Miguel Cordova, Milind Rajadhyaksha, and Christopher A. Barker "Guiding skin cancer therapy with combined confocal-OCT imaging", Proc. SPIE PC12368, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XXI, PC1236807 (6 March 2023); https://doi.org/10.1117/12.2649339

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KEYWORDS

Skin cancer

Optical coherence tomography

Image resolution

Skin

Confocal microscopy

Diagnostics

Radio optics

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